Mouse LSR (Lipolysis Stimulated Lipoprotein Receptor) Sandwich ELISA Kit (STJE0010432)
SPECIFICATIONS
General Information
| Short Description | This LSR Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.055ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Lsr |
| Gene ID | 54135 |
| Uniprot ID | LSR_MOUSE |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in epithelial tissues (at protein level). Specifically expressed in liver and to a lower extent in kidney (at protein level). Also detected in brain, testis, ovaries, adrenal gland, intestine, muscle, and lung. In colon, only expressed in the lower portion of crypts. Expressed in the liver. Isoform 2: Expressed in liver, stomach, small intestine and colon. Also detected in other epithelial tissues. |
| Post Translational Modifications | Phosphorylation at Ser-308 by MAPK8/JNK1 and MAPK9/JNK2 may be required for exclusive localization at tricellular tight junstions. Polyubiquitinated at Lys-583 via 'Lys-63'-linked ubiquitin chains.deubiquitinated by USP53. |
| Function | Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. Maintains epithelial barrier function by recruiting MARVELD2/tricellulin to tricellular tight junctions. |
| Protein Name | Lipolysis-Stimulated Lipoprotein ReceptorAngulin-3Lipolysis-Stimulated ReceptorLiver-Specific Bhlh-Zip Transcription FactorLiver-Specific Gene On Mouse Chromosome 7 Protein |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionTight JunctionLocated At Tricellular Contacts |
| Alternative ELISA Names | Lipolysis-Stimulated Lipoprotein Receptor ELISA kitAngulin-3 ELISA kitLipolysis-Stimulated Receptor ELISA kitLiver-Specific Bhlh-Zip Transcription Factor ELISA kitLiver-Specific Gene On Mouse Chromosome 7 Protein ELISA kitLsr ELISA kitIldr3 ELISA kitLisch7 ELISA kit |
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Information sourced from Uniprot.org