Mouse LIFR (CD118) protein (Recombinant) (STJP000544)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding extracellular domain of mouse CD118 (LIFR) including a C-terminal 6His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Mouse LIFR (CD118)-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | 0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction | Can be stored in working aliquots at 2ยฐC-8ยฐC C for one month, or at-20ยฐC to-70ยฐC for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/ยตg (1EU/ยตg). NA |
Target Information
| Gene Symbol | LIFR |
| Gene ID | 3977 |
| Uniprot ID | LIFR_HUMAN |
| Immunogen | Optimized DNA sequence encoding extracellular domain of mouse CD118 (LIFR) including a C-terminal 6His tag was expressed in HEK293 cells. NA |
| Immunogen Region | ECD |
Additional Info
| Function | Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. |
| Protein Name | Leukemia Inhibitory Factor ReceptorLif ReceptorLif-RCd Antigen Cd118 |
| Database Links | Reactome: R-HSA-6788467Reactome: R-HSA-8939247 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Protein Names | Leukemia Inhibitory Factor Receptor proteinLif Receptor proteinLif-R proteinCd Antigen Cd118 proteinLIFR protein |
Information sourced from Uniprot.org