Mouse L-Selectin/SELL/CD62L protein (Recombinant) (C-His) (STJP020360)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Mouse L-Selectin/SELL/CD62L Protein is produced by HEK293 cells system. The target protein is expressed with sequence (Met1-Asn332) of Mouse L-Selectin/SELL/CD62L (Accession #NP_035476.1) fused with His tag at the C-Terminus.
General Information
| Short Description | Recombinant-Mouse L-Selectin/SELL/CD62L-C-His protein was developed in hek293 cells using the region Met1-Asn332. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.01 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | SELL |
| Gene ID | 6402 |
| Uniprot ID | LYAM1_HUMAN |
| Immunogen | Recombinant Mouse L-Selectin/SELL/CD62L Protein is produced by HEK293 cells system. The target protein is expressed with sequence (Met1-Asn332) of Mouse L-Selectin/SELL/CD62L (Accession #NP_035476.1) fused with His tag at the C-Terminus. |
| Immunogen Region | Met1-Asn332 |
| Immunogen Sequence | DFLAHHGTDCWTYHYSEKPM NWQRARRFCRDNYTDLVAIQ NKAEIEYLEKTLPFSRSYYW IGIRKIGGIWTWVGTNKSLT EEAENWGDGEPNNKKNKEDC VEIYIKRNKDAGKWNDDACH KLKAALCYTASCQPWSCSGH GECVEIINNYTCNCDVGYYG PQCQFVIQCEPLEAPELGTM DCTHPLGNFSFSSQCAFSCS EGTNLTGIEETTCGPFGNWS SPEPTCQVIQCEPLSAPDL |
Additional Info
| Tissue Specificity | Expressed in B-cell lines and T-lymphocytes. |
| Post Translational Modifications | N-glycosylated. |
| Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. |
| Protein Name | L-SelectinCd62 Antigen-Like Family Member LLeukocyte Adhesion Molecule 1Lam-1Leukocyte Surface Antigen Leu-8Leukocyte-Endothelial Cell Adhesion Molecule 1Lecam1Lymph Node Homing ReceptorTq1Gp90-MelCd Antigen Cd62l |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | L-Selectin proteinCd62 Antigen-Like Family Member L proteinLeukocyte Adhesion Molecule 1 proteinLam-1 proteinLeukocyte Surface Antigen Leu-8 proteinLeukocyte-Endothelial Cell Adhesion Molecule 1 proteinLecam1 proteinLymph Node Homing Receptor proteinTq1 proteinGp90-Mel proteinCd Antigen Cd62l proteinSELL proteinLNHR proteinLYAM1 protein |
Information sourced from Uniprot.org