Mouse KARS (Lysyl tRNA Synthetase) Sandwich ELISA Kit (STJE0010133)
SPECIFICATIONS
General Information
| Short Description | This KARS Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.086ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Kars1 |
| Gene ID | 85305 |
| Uniprot ID | SYK_MOUSE |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylated on a serine residue after mast cell stimulation with immunoglobulin E (IgE). |
| Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. |
| Protein Name | Lysine--Trna LigaseLysyl-Trna SynthetaseLysrs |
| Database Links | Reactome: R-MMU-9856649 |
| Cellular Localisation | CytoplasmCytosolNucleusCell MembranePeripheral Membrane ProteinSecretedSecretion Is Induced By Tnf-AlphaCytosolic In Quiescent Mast CellsTranslocates Into The Nucleus In Response To Mast Cell Activation By Immunoglobulin E |
| Alternative ELISA Names | Lysine--Trna Ligase ELISA kitLysyl-Trna Synthetase ELISA kitLysrs ELISA kitKars1 ELISA kitKars ELISA kit |
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Information sourced from Uniprot.org