Applications: |
ELISA |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: |
0.049ng/mL |
Detection Limit: |
0.156-10ng/mL |
Short Description: |
This ITPA Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids. |
Storage Instruction: |
Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: |
4.5 hrs |
Gene Symbol: |
Itpa |
Gene ID: |
16434 |
Uniprot ID: |
ITPA_MOUSE |
Sample Type: |
tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. |
Protein Name | Inosine Triphosphate PyrophosphataseItpaseInosine TriphosphataseNon-Canonical Purine Ntp PyrophosphataseNon-Standard Purine Ntp PyrophosphataseNucleoside-Triphosphate DiphosphataseNucleoside-Triphosphate PyrophosphataseNtpase |
Database Links | Reactome: R-MMU-74259Reactome: -MMU-9755088 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Inosine Triphosphate Pyrophosphatase ELISA kitItpase ELISA kitInosine Triphosphatase ELISA kitNon-Canonical Purine Ntp Pyrophosphatase ELISA kitNon-Standard Purine Ntp Pyrophosphatase ELISA kitNucleoside-Triphosphate Diphosphatase ELISA kitNucleoside-Triphosphate Pyrophosphatase ELISA kitNtpase ELISA kitItpa ELISA kit |
output | |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance