Mouse IQGAP1 (IQ Motif Containing GTPase Activating Protein 1) Sandwich ELISA Kit (STJE0010044)
SPECIFICATIONS
General Information
| Short Description | This IQGAP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.136ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Iqgap1 |
| Gene ID | 29875 |
| Uniprot ID | IQGA1_MOUSE |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in the kidney (at protein level). |
| Post Translational Modifications | |
| Function | Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Recruited to the cell cortex by interaction with ILK which allows it to cooperate with its effector DIAPH1 to locally stabilize microtubules and allow stable insertion of caveolae into the plasma membrane. Binds to activated CDC42 but does not stimulate its GTPase activity. Associates with calmodulin. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest. |
| Protein Name | Ras Gtpase-Activating-Like Protein Iqgap1 |
| Database Links | Reactome: R-MMU-373753Reactome: -MMU-5626467Reactome: -MMU-5674135Reactome: -MMU-6798695Reactome: -MMU-8980692Reactome: -MMU-9013106Reactome: -MMU-9013149Reactome: -MMU-9013404Reactome: -MMU-9013406Reactome: -MMU-9013420Reactome: -MMU-9013424 |
| Cellular Localisation | Cell MembraneNucleusCytoplasmCell CortexApical Cell MembraneBasolateral Cell MembraneSubcellular Distribution Is Regulated By The Cell CycleNuclear Levels Increase At G1/S Phase |
| Alternative ELISA Names | Ras Gtpase-Activating-Like Protein Iqgap1 ELISA kitIqgap1 ELISA kit |
| output |
Information sourced from Uniprot.org