| Host: |
HEK293 |
| Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse Interleukin-18 Binding Protein (IL-18BP)-protein was developed from hek293. For use in research applications. |
| Conjugation: |
Unconjugated |
| Formulation: |
0.2 Mu m filtered PBS solution. |
| Dilution Range: |
To prepare stock, a quick spin of the vial followed by reconstitution in distilled water to a concentration not less than.1 mg/mL. |
| Storage Instruction: |
Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: |
The activity of recombinant Interleukin-18 Binding Protein was determined by the ability to bind IL-18 in functional ELISA. NA |
| Gene Symbol: |
Il18bp |
| Gene ID: |
16068 |
| Uniprot ID: |
I18BP_MOUSE |
| Immunogen Region: |
Mature chain |
| Immunogen: |
Optimized DNA sequence encoding Mouse Interleukin-18 Binding Protein (IL-18BP) mature chain fused to an C-terminal polyHis tag was expressed in HEK cells. NA |
| Immunogen Sequence: |
MTMRHCWTAG PSSWWVLLLY VHVILARATS APQTTATVLT GSSKDPCSSW SPAVPTKQYP ALDVIWPEKE VPLNGTLTLS CTACSRFPYF SILYWLGNGS FIEHLPGRLK EGHTSREHRN TSTWLHRALV LEELSPTLRS TNFSCLFVDP GQVAQYHIIL AQLWDGLKTA PSPSQETLSS HSPVSRSAGP GVA NA |
| Function | Binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. |
| Protein Name | Interleukin-18-Binding ProteinIl-18bpInterferon Gamma-Inducing Factor-Binding Protein |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interleukin-18-Binding Protein proteinIl-18bp proteinInterferon Gamma-Inducing Factor-Binding Protein proteinIl18bp proteinIgifbp protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
