Mouse IL5Ra (Interleukin 5 Receptor Alpha) Sandwich ELISA Kit (STJE0009954)
SPECIFICATIONS
General Information
| Short Description | This IL5Ra Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 28.5pg/mL |
| Detection Limit | 62.5-4000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Il5ra |
| Gene ID | 16192 |
| Uniprot ID | IL5RA_MOUSE |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed on eosinophils and basophils. Also on B-cells. |
| Post Translational Modifications | |
| Function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway. |
| Protein Name | Interleukin-5 Receptor Subunit AlphaIl-5 Receptor Subunit AlphaIl-5r Subunit AlphaIl-5r-AlphaIl-5raCd Antigen Cd125 |
| Database Links | Reactome: R-MMU-512988Reactome: -MMU-5673001Reactome: -MMU-912526 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative ELISA Names | Interleukin-5 Receptor Subunit Alpha ELISA kitIl-5 Receptor Subunit Alpha ELISA kitIl-5r Subunit Alpha ELISA kitIl-5r-Alpha ELISA kitIl-5ra ELISA kitCd Antigen Cd125 ELISA kitIl5ra ELISA kitIl5r ELISA kit |
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Information sourced from Uniprot.org