Mouse IL-31R beta (OSMRb) protein (Recombinant) (STJP000293)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding extracellular domain of mouse Interleukin-31 receptor beta subunit (OSM-Rb) including a C-terminal tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Mouse IL-31R beta (OSMRb)-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | 0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | Osmr |
| Gene ID | 18414 |
| Uniprot ID | OSMR_MOUSE |
| Immunogen | Optimized DNA sequence encoding extracellular domain of mouse Interleukin-31 receptor beta subunit (OSM-Rb) including a C-terminal tag was expressed in HEK293 cells. NA |
| Immunogen Region | ECD |
Additional Info
| Tissue Specificity | Widely expressed. Expressed at highest levels in the lung, heart, thymus and spleen. Expressed in dorsal root ganglia. |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Protein Name | Oncostatin-M-Specific Receptor Subunit BetaInterleukin-31 Receptor Subunit BetaIl-31 Receptor Subunit BetaIl-31r Subunit BetaIl-31r-BetaIl-31rb |
| Database Links | Reactome: R-MMU-6788467 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Oncostatin-M-Specific Receptor Subunit Beta proteinInterleukin-31 Receptor Subunit Beta proteinIl-31 Receptor Subunit Beta proteinIl-31r Subunit Beta proteinIl-31r-Beta proteinIl-31rb proteinOsmr proteinOsmrb protein |
Information sourced from Uniprot.org