Mouse HEXa (Hexosaminidase A Alpha) Sandwich ELISA Kit (STJE0009438)
SPECIFICATIONS
General Information
| Short Description | This HEXa Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.051ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Hexa |
| Gene ID | 15211 |
| Uniprot ID | HEXA_MOUSE |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Ubiquitous. Most abundant in testis, adrenal, epididymis and heart. Low levels seen in the liver. |
| Post Translational Modifications | |
| Function | Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. |
| Protein Name | Beta-Hexosaminidase Subunit AlphaBeta-N-Acetylhexosaminidase Subunit AlphaHexosaminidase Subunit AN-Acetyl-Beta-Glucosaminidase Subunit Alpha |
| Database Links | Reactome: R-MMU-2022857Reactome: -MMU-2024101Reactome: -MMU-2160916Reactome: -MMU-9840310 |
| Cellular Localisation | Lysosome |
| Alternative ELISA Names | Beta-Hexosaminidase Subunit Alpha ELISA kitBeta-N-Acetylhexosaminidase Subunit Alpha ELISA kitHexosaminidase Subunit A ELISA kitN-Acetyl-Beta-Glucosaminidase Subunit Alpha ELISA kitHexa ELISA kit |
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Information sourced from Uniprot.org