Mouse HADHb (Hydroxyacyl Coenzyme A Dehydrogenase Beta) Sandwich ELISA Kit (STJE0009386)
SPECIFICATIONS
General Information
| Short Description | This HADHb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.115ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Hadhb |
| Gene ID | 231086 |
| Uniprot ID | ECHB_MOUSE |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Acetylation of Lys-202 is observed in liver mitochondria from fasted mice but not from fed mice. |
| Function | Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity. |
| Protein Name | Trifunctional Enzyme Subunit Beta - MitochondrialTp-Beta Includes - 3-Ketoacyl-Coa ThiolaseAcetyl-Coa AcyltransferaseBeta-Ketothiolase |
| Database Links | Reactome: R-MMU-1482798Reactome: -MMU-77285Reactome: -MMU-77305Reactome: -MMU-77310Reactome: -MMU-77346Reactome: -MMU-77348Reactome: -MMU-77350 |
| Cellular Localisation | MitochondrionMitochondrion Inner MembraneMitochondrion Outer MembraneEndoplasmic ReticulumProtein Stability And Association With Membranes Require Hadha |
| Alternative ELISA Names | Trifunctional Enzyme Subunit Beta - Mitochondrial ELISA kitTp-Beta Includes - 3-Ketoacyl-Coa Thiolase ELISA kitAcetyl-Coa Acyltransferase ELISA kitBeta-Ketothiolase ELISA kitHadhb ELISA kit |
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Information sourced from Uniprot.org