Tissue Specificity | Expressed in the liver, skin and kidney. |
Post Translational Modifications | |
Function | Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid. |
Protein Name | Glutathione S-Transferase A113-Hydroperoxyoctadecadienoate PeroxidaseAndrost-5-Ene-3 -17-Dione IsomeraseGst Class-Alpha Member 1Glutathione S-Transferase YaGlutathione S-Transferase Ya1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed |
Database Links | Reactome: R-MMU-156590Reactome: -MMU-189483Reactome: -MMU-9748787 |
Cellular Localisation | |
Alternative ELISA Names | Glutathione S-Transferase A1 ELISA kit13-Hydroperoxyoctadecadienoate Peroxidase ELISA kitAndrost-5-Ene-3 -17-Dione Isomerase ELISA kitGst Class-Alpha Member 1 ELISA kitGlutathione S-Transferase Ya ELISA kitGlutathione S-Transferase Ya1 Cleaved Into - Glutathione S-Transferase A1 - N-Terminally Processed ELISA kitGsta1 ELISA kitGsta ELISA kitGstya ELISA kit |
output | |
Information sourced from Uniprot.org