Mouse GHRL protein (Recombinant) (N-GST & C-His) (STJP015324)
SPECIFICATIONS
HostE.coli
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse GHRL-N-GST & C-His protein was developed from e.coli for the region N-GST & C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | Ghrl |
| Gene ID | 58991 |
| Uniprot ID | GHRL_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Leu28-Lys117 |
Additional Info
| Post Translational Modifications | O-octanoylated by GOAT/MBOAT4. O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated form ghrelin-C10 differs in the length of the carbon backbone of the carboxylic acid bound to Ser-26. Amidation of Leu-98 is essential for obestatin activity. |
| Function | Ghrelin: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. |
| Protein Name | Appetite-Regulating HormoneGrowth Hormone SecretagogueGrowth Hormone-Releasing PeptideMotilin-Related PeptideProtein M46 Cleaved Into - Ghrelin - Obestatin |
| Database Links | Reactome: R-MMU-416476Reactome: -MMU-422085 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Appetite-Regulating Hormone proteinGrowth Hormone Secretagogue proteinGrowth Hormone-Releasing Peptide proteinMotilin-Related Peptide proteinProtein M46 Cleaved Into - Ghrelin - Obestatin proteinGhrl proteinMtlrp protein |
Information sourced from Uniprot.org