• Biotinylated Mouse GFRAL on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Mouse GFRAL is greater than 95% as determined by SEC-HPLC.
  • Immobilized Biotinylated Mouse GFRAL, His Tag at 0. 5 Mu g/ml (100 Mu l/Well) on streptavidin (5 Mu g/ml) precoated plate. Dose response curve for Mouse GDF15, hFc Tag with the EC50 of 6. 2ng/ml determined by ELISA.

Mouse GFRAL/GFR alpha-like protein (Recombinant) (N-His-Avi) {Biotin} (STJP001652)

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STJP001652

£696.50 - £2,171.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse GFRAL/GFR alpha-like-N-His-Avi protein was developed from hek293 and has a target region of N-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: Gfral
Gene ID: 404194
Uniprot ID: GFRAL_MOUSE
Immunogen Region: Gln20-Glu350
Immunogen: DNA sequence encoding Mouse GFRAL/GFR alpha-like including a N-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Function Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Protein Name Gdnf Family Receptor Alpha-Like
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Extracellular Side
Alternative Protein Names Gdnf Family Receptor Alpha-Like protein
Gfral protein
Gral protein

Information sourced from Uniprot.org

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