Mouse FBXL3 (F-Box And Leucine Rich Repeat Protein 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015199)
SPECIFICATIONS
General Information
| Short Description | This FBXL3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.059ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Fbxl3 |
| Gene ID | 50789 |
| Uniprot ID | FBXL3_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Ubiquitously expressed but enriched in brain. Diffusely expressed in the suprachiasmatic nucleus, SCN. |
| Post Translational Modifications | Undergoes autophagy-mediated degradation in the liver in a time-dependent manner. |
| Function | Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex. |
| Protein Name | F-Box/Lrr-Repeat Protein 3F-Box And Leucine-Rich Repeat Protein 3aF-Box/Lrr-Repeat Protein 3aProtein After-HoursProtein Overtime |
| Database Links | Reactome: R-MMU-8951664Reactome: -MMU-983168 |
| Cellular Localisation | NucleusCytoplasmPredominantly Nuclear |
| Alternative ELISA Names | F-Box/Lrr-Repeat Protein 3 ELISA kitF-Box And Leucine-Rich Repeat Protein 3a ELISA kitF-Box/Lrr-Repeat Protein 3a ELISA kitProtein After-Hours ELISA kitProtein Overtime ELISA kitFbxl3 ELISA kitAfh ELISA kitFbl3a ELISA kitFbxl3a ELISA kitOvtm ELISA kit |
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Information sourced from Uniprot.org