Mouse ENSa (Endosulfine Alpha) Sandwich ELISA Kit (STJE0008652)
SPECIFICATIONS
General Information
| Short Description | This ENSa Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.065ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Ensa |
| Gene ID | 56205 |
| Uniprot ID | ENSA_MOUSE |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Present in striatum (at protein level). |
| Post Translational Modifications | Phosphorylation at Ser-67 by GWL during mitosis is essential for interaction with PPP2R2D (PR55-delta) and subsequent inactivation of PP2A. Phosphorylated by PKA. |
| Function | Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents. |
| Protein Name | Alpha-EndosulfineArpp-19e |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Alpha-Endosulfine ELISA kitArpp-19e ELISA kitEnsa ELISA kit |
| output |
Information sourced from Uniprot.org