| Host: | Insect cells |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse EGFL7-protein was developed from insect cells. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution pH 7.4. |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: | The activity was determined by the ability to support adhesion of HUVEC cells. NA |
| Gene Symbol: | Egfl7 |
| Gene ID: | 353156 |
| Uniprot ID: | EGFL7_MOUSE |
| Immunogen Region: | C-Term |
| Immunogen: | DNA sequence encoding mature chain of Mouse EGFL7 (VE-Statin) isoform-1 to a C-terminal polyHis tag was expressed in Insect cells. NA |
| Tissue Specificity | Expressed specifically by endothelial cells of the highly vascularized organs heart, lung and kidney. |
| Function | Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis. |
| Protein Name | Epidermal Growth Factor-Like Protein 7Egf-Like Protein 7Multiple Epidermal Growth Factor-Like Domains Protein 7Multiple Egf-Like Domains Protein 7Notch4-Like ProteinVascular Endothelial StatinVe-StatinZneu1 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Protein Names | Epidermal Growth Factor-Like Protein 7 proteinEgf-Like Protein 7 proteinMultiple Epidermal Growth Factor-Like Domains Protein 7 proteinMultiple Egf-Like Domains Protein 7 proteinNotch4-Like Protein proteinVascular Endothelial Statin proteinVe-Statin proteinZneu1 proteinEgfl7 proteinMegf7 protein |
Information sourced from Uniprot.org