Mouse DUSP1 (Dual Specificity Phosphatase 1) Sandwich ELISA Kit (STJE0008531)
SPECIFICATIONS
General Information
| Short Description | This DUSP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 13.2pg/mL |
| Detection Limit | 31.2-2000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Dusp1 |
| Gene ID | 19252 |
| Uniprot ID | DUS1_MOUSE |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation. 'Lys-48'-linked polyubiquitinated by NEURL3, leading to proteasomal degradation. |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle. |
| Protein Name | Dual Specificity Protein Phosphatase 1Mitogen-Activated Protein Kinase Phosphatase 1Map Kinase Phosphatase 1Mkp-1Protein-Tyrosine Phosphatase 3ch134Protein-Tyrosine Phosphatase Erp |
| Database Links | Reactome: R-MMU-112409Reactome: -MMU-5675221 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Dual Specificity Protein Phosphatase 1 ELISA kitMitogen-Activated Protein Kinase Phosphatase 1 ELISA kitMap Kinase Phosphatase 1 ELISA kitMkp-1 ELISA kitProtein-Tyrosine Phosphatase 3ch134 ELISA kitProtein-Tyrosine Phosphatase Erp ELISA kitDusp1 ELISA kit3ch134 ELISA kitMkp1 ELISA kitPtpn10 ELISA kitPtpn16 ELISA kit |
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Information sourced from Uniprot.org