Mouse DKK1 (Dickkopf Related Protein 1) Sandwich ELISA Kit (STJE0007242)
SPECIFICATIONS
General Information
| Short Description | This DKK1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.125ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Dkk1 |
| Gene ID | 13380 |
| Uniprot ID | DKK1_MOUSE |
| Sample Type | serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Plays a role in limb development.attenuates Wnt signaling in the developing limb to allow normal limb patterning. |
| Protein Name | Dickkopf-Related Protein 1Dickkopf-1Dkk-1Mdkk-1 |
| Database Links | Reactome: R-MMU-3772470 |
| Cellular Localisation | Secreted |
| Alternative ELISA Names | Dickkopf-Related Protein 1 ELISA kitDickkopf-1 ELISA kitDkk-1 ELISA kitMdkk-1 ELISA kitDkk1 ELISA kit |
| output |
Information sourced from Uniprot.org