Mouse CTSB (Cathepsin B) Antibody Pair (STJAP00557)
General Information
| Short Description | This CTSB antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | Ctsb |
| Gene ID | 13030 |
| Uniprot ID | CATB_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse CTSB protien.Detection Immunogen: Recombinant Mouse CTSB protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. |
| Protein Name | Cathepsin BCathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain |
| Database Links | Reactome: R-MMU-1442490Reactome: -MMU-1679131Reactome: -MMU-2022090Reactome: -MMU-2132295Reactome: -MMU-6798695 |
| Cellular Localisation | LysosomeMelanosomeSecretedExtracellular SpaceApical Cell MembranePeripheral Membrane ProteinExtracellular SideLocalizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells |
| Alternative Antibody Pair Names | Cathepsin B antibody pairCathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain antibody pairCtsb antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse CTSB (Cathepsin B) Antibody Pair (STJAP00557)
This antibody pair is validated to detect mouse Cathepsin B (CTSB), corresponding to UniProt accession P10605. Reactivity has been confirmed for mouse samples only.
Both antibodies are rabbit-derived and antigen affinity-purified, supplied at 0.5 mg/mL. The capture antibody is unconjugated, formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is biotinylated and formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5.
This antibody pair is validated for use in ELISA. It is intended for the quantitative detection of mouse CTSB in serum, plasma, and other biological fluid samples.
Both the capture and detection antibodies were raised against recombinant mouse CTSB protein. No specific immunogen region is indicated in the product documentation.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain antibody integrity and performance.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.