Mouse CHI3L1 (Chitinase-3-Like Protein 1) Antibody Pair (STJAP00571)
General Information
| Short Description | This CHI3L1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Sheep/Sheep |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | Chi3l1 |
| Gene ID | 12654 |
| Uniprot ID | CH3L1_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse CHI3L1 protien.Detection Immunogen: Recombinant Mouse CHI3L1 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Function | Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung. |
| Protein Name | Chitinase-3-Like Protein 1Brp39 ProteinBreast Regression Protein 39Cartilage Glycoprotein 39Cgp-39Gp-39 |
| Database Links | Reactome: R-MMU-6798695 |
| Cellular Localisation | SecretedExtracellular SpaceCytoplasmEndoplasmic ReticulumDetected In Bronchoalveolar Lavage (Bal) FluidsLocalizes Mainly To Endoplasmic Reticulum When Overexpressed In CellsWith Some Protein Also Detected Throughout The Cytoplasm |
| Alternative Antibody Pair Names | Chitinase-3-Like Protein 1 antibody pairBrp39 Protein antibody pairBreast Regression Protein 39 antibody pairCartilage Glycoprotein 39 antibody pairCgp-39 antibody pairGp-39 antibody pairChi3l1 antibody pairBrp39 antibody pairChil1 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse CHI3L1 (Chitinase-3-Like Protein 1) Antibody Pair (STJAP00571)
This antibody pair is designed to detect mouse CHI3L1 (Chitinase-3-Like Protein 1), corresponding to UniProt entry Q61362. Reactivity has been specified for mouse samples only.
The capture antibody is supplied unconjugated, while the detection antibody is biotin-conjugated. Both are sheep-derived, purified by antigen affinity, and supplied at a concentration of 0.5 mg/mL.
This antibody pair has been validated for use in ELISA. It is intended for sandwich ELISA-based detection of mouse CHI3L1 in serum, plasma, and other biological fluid samples.
Both the capture and detection antibodies were raised against recombinant mouse CHI3L1 protein. Both were subsequently purified by antigen affinity chromatography.
Both components should be stored at -20°C for long-term storage, and freeze-thaw cycles should be avoided. Both formulations contain 50% glycerol and 0.04% Proclin 300 as stabilizers and preservatives.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.