| Host: |
HEK293 cells |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Recombinant-Mouse CD70/TNFSF7/CD27 Ligand-N-his protein was developed from hek293 cells and has a target region of N-his. For use in research applications. |
| Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Cd70 |
| Gene ID: |
21948 |
| Uniprot ID: |
CD70_MOUSE |
| Immunogen Region: |
Glu53-Arg195 |
| Immunogen: |
Recombinant Mouse CD70/TNFSF7/CD27 Ligand Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu53-Arg195) of Mouse CD70/TNFSF7/CD27 Ligand (Accession #NP_035747.1) fused with a His tag at the N-term |
| Post Translational Modifications | N-glycosylated. |
| Function | Cytokine which is the ligand for CD27. The CD70-CD27 pathway plays an important role in the generation and maintenance of T cell immunity, in particular during antiviral responses. Upon CD27 binding, induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. |
| Protein Name | Cd70 AntigenCd27 LigandCd27-LTumor Necrosis Factor Ligand Superfamily Member 7Cd Antigen Cd70 |
| Database Links | Reactome: R-MMU-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Cd70 Antigen proteinCd27 Ligand proteinCd27-L proteinTumor Necrosis Factor Ligand Superfamily Member 7 proteinCd Antigen Cd70 proteinCd70 proteinCd27l proteinCd27lg proteinTnfsf7 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
