Human CD70 protein (Recombinant) (N-His) (STJP009267)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD70-N-His protein was developed from mammalian cells for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CD70 |
| Gene ID | 970 |
| Uniprot ID | CD70_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln39-Pro193 |
Additional Info
| Function | Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells. |
| Protein Name | Cd70 AntigenCd27 LigandCd27-LTumor Necrosis Factor Ligand Superfamily Member 7Cd Antigen Cd70 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Cd70 Antigen proteinCd27 Ligand proteinCd27-L proteinTumor Necrosis Factor Ligand Superfamily Member 7 proteinCd Antigen Cd70 proteinCD70 proteinCD27L proteinCD27LG proteinTNFSF7 protein |
Information sourced from Uniprot.org