Mouse CD39L2/ENTPD6 protein (Recombinant) (His-Tag) (STJP019452)

SPECIFICATIONS
HostHEK293 Cells
ImmunogenMouse
STJP019452
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General Information

Short DescriptionRecombinant-Mouse CD39L2/ENTPD6-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Enzyme Activity
HostHEK293 Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid In Phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin< 1 EU per 1ug of protein (determined by LAL method)
ImmunoreactivitySpecific activity is > 80, 000 pmol/min/ug, and is defined as the amount of enzyme that hydrolyze GDP per minute at pH 7.5 at 25C.

Target Information

Gene SymbolEntpd6
Gene ID12497
Uniprot IDENTP6_MOUSE
Accession NumberNP_742115.2
ImmunogenMouse
Immunogen Region33-455aa
Immunogen SequenceKWHRAS AAQAFFTIAG AASGARWTQQ AFSSPGSAAR GHEVFYGIMF DAGSTGTRIH VFQFARPPGE TPTLTHETFK ALKPGLSAYA DDVEKSAQGI QELLNVAKQH IPYDFWKATP LVLKATAGLR LLPGEKAQKL LQKVKEVFKA SPFLVGDDCV SIMNGTDEGV SAWITVNFLT GSLKTPGSSS VGMLDLGGGS TQITFLPRVE GTLQASPPGH LTALQM

Additional Info

Post Translational Modifications N-glycosylated.
Function Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP. The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides.
Protein Name Ectonucleoside Triphosphate Diphosphohydrolase 6
Ntpdase 6
Cd39 Antigen-Like 2
Database Links Reactome: R-MMU-8850843
Cellular Localisation Golgi Apparatus Membrane
Single-Pass Type Ii Membrane Protein
Secreted
Cell Membrane
Exists As A Secreted And Membrane-Bound Forms In The Medium Of Transfected Cells
The Secreted Form Is Predominant
Alternative Protein Names Ectonucleoside Triphosphate Diphosphohydrolase 6 protein
Ntpdase 6 protein
Cd39 Antigen-Like 2 protein
Entpd6 protein
Cd39l2 protein

Information sourced from Uniprot.org

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