Mouse CD365/KIM-1/TIM-1/HAVCR1 protein (Recombinant) (C-His) (STJP013992)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse CD365/KIM-1/TIM-1/HAVCR1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | Havcr1 |
| Gene ID | 171283 |
| Uniprot ID | HAVR1_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Tyr22-Thr212 |
Additional Info
| Function | Phosphatidylserine receptor that plays an important functional role in regulatory B-cells homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. May play a role in kidney injury and repair. |
| Protein Name | Hepatitis A Virus Cellular Receptor 1 HomologHavcr-1Kidney Injury Molecule 1Kim-1T Cell Immunoglobulin And Mucin Domain-Containing Protein 1Timd-1T Cell Membrane Protein 1T-Cell Immunoglobulin Mucin Receptor 1Tim-1Cd Antigen Cd365 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Hepatitis A Virus Cellular Receptor 1 Homolog proteinHavcr-1 proteinKidney Injury Molecule 1 proteinKim-1 proteinT Cell Immunoglobulin And Mucin Domain-Containing Protein 1 proteinTimd-1 proteinT Cell Membrane Protein 1 proteinT-Cell Immunoglobulin Mucin Receptor 1 proteinTim-1 proteinCd Antigen Cd365 proteinHavcr1 proteinKim1 proteinTim1 proteinTimd1 protein |
Information sourced from Uniprot.org