Mouse CD276 protein (Recombinant) (C-6His) (STJP002881)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Mouse CD276 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val 29-Phe 244) of mouse CD276 (Accession #NP_598744.1) fused with and a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Mouse CD276-C-6His protein was developed in hek293 cells using the region Val 29-Phe 244. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Measured by its binding ability in a functional ELISA.Immobilized Mouse CD276 at 2 Mu g/mL (100 Mu L/well) can bind CD276 Rabbit pAb with a linear range of 1-274 ng/mL. |
| Determination Method | <0.1 EU/Mu g |
Target Information
| Gene Symbol | Cd276 |
| Gene ID | 102657 |
| Uniprot ID | CD276_MOUSE |
| Immunogen | Recombinant Mouse CD276 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val 29-Phe 244) of mouse CD276 (Accession #NP_598744.1) fused with and a 6×His tag at the C-terminus. |
| Immunogen Region | Val 29-Phe 244 |
| Immunogen Sequence | VEVQVSEDPVVALVDTDATL RCSFSPEPGFSLAQLNLIWQ LTDTKQLVHSFTEGRDQGSA YSNRTALFPDLLVQGNASLR LQRVRVTDEGSYTCFVSIQD FDSAAVSLQVAAPYSKPSMT LEPNKDLRPGNMVTITCSSY QGYPEAEVFWKDGQGVPLTG NVTTSQMANERGLFDVHSVL RVVLGANGTYSCLVRNPVLQ QDAHGSVTITGQPLTF |
Additional Info
| Function | Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. |
| Protein Name | Cd276 AntigenB7 Homolog 3B7-H3Costimulatory MoleculeCd Antigen Cd276 |
| Database Links | |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cd276 Antigen proteinB7 Homolog 3 proteinB7-H3 proteinCostimulatory Molecule proteinCd Antigen Cd276 proteinCd276 proteinB7h3 protein |
Information sourced from Uniprot.org