Mouse CD275/B7-H2 protein (Recombinant) (C-His) (STJP013773)

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STJP013773-100
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Short Description :Recombinant-Mouse CD275/B7-H2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:Icoslg
Gene ID:50723
Uniprot ID:ICOSL_MOUSE
Immunogen:Mus musculus (Mouse)
Immunogen Region:Glu47-Lys279
Function Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion.also induces B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (Probable). During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype.
Protein Name Icos Ligand
B7 Homolog 2
B7-H2
B7-Like Protein Gl50
B7-Related Protein 1
B7rp-1
Licos
Cd Antigen Cd275
Database Links Reactome: R-MMU-9927354
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Isoform 2: Cell Membrane
Alternative Protein Names Icos Ligand protein
B7 Homolog 2 protein
B7-H2 protein
B7-Like Protein Gl50 protein
B7-Related Protein 1 protein
B7rp-1 protein
Licos protein
Cd Antigen Cd275 protein
Icoslg protein
B7h protein
B7h2 protein
B7rp1 protein
Icosl protein

Information sourced from Uniprot.org