Mouse CD275/B7-H2 protein (Recombinant) (C-His) (STJP013773)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse CD275/B7-H2-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | Icoslg |
| Gene ID | 50723 |
| Uniprot ID | ICOSL_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Glu47-Lys279 |
Additional Info
| Function | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion.also induces B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (Probable). During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype. |
| Protein Name | Icos LigandB7 Homolog 2B7-H2B7-Like Protein Gl50B7-Related Protein 1B7rp-1LicosCd Antigen Cd275 |
| Database Links | Reactome: R-MMU-9927354 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 1: Cell MembraneIsoform 2: Cell Membrane |
| Alternative Protein Names | Icos Ligand proteinB7 Homolog 2 proteinB7-H2 proteinB7-Like Protein Gl50 proteinB7-Related Protein 1 proteinB7rp-1 proteinLicos proteinCd Antigen Cd275 proteinIcoslg proteinB7h proteinB7h2 proteinB7rp1 proteinIcosl protein |
Information sourced from Uniprot.org