Host: |
HEK293 |
Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Mouse CD27 (TNFRSF7)-protein was developed from hek293. For use in research applications. |
Conjugation: |
Unconjugated |
Formulation: |
Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Storage Instruction: |
Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: |
The activity was tested by the ability of immobilized recombinant Mouse CD27 to bind Human CD70 with a linear range of 0.08-1 ng/ml NA |
Gene Symbol: |
Cd27 |
Gene ID: |
21940 |
Uniprot ID: |
CD27_MOUSE |
Immunogen Region: |
ECD |
Immunogen: |
Optimized DNA sequence encoding extracellular domain of Mouse CD27 including a C-terminal His tag was expressed in HEK293 cells. NA |
Tissue Specificity | In thymus and spleen, but not in non-lymphoid tissues. |
Function | Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
Protein Name | Cd27 AntigenCd27l ReceptorT-Cell Activation Antigen Cd27Tumor Necrosis Factor Receptor Superfamily Member 7Cd Antigen Cd27 |
Database Links | Reactome: R-MMU-5669034 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Cd27 Antigen proteinCd27l Receptor proteinT-Cell Activation Antigen Cd27 proteinTumor Necrosis Factor Receptor Superfamily Member 7 proteinCd Antigen Cd27 proteinCd27 proteinTnfrsf7 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance