| Short Description : | Recombinant-Mouse CD200R1-C-hFc & Avi protein was developed in hek293 cells using the region Thr26-Pro238. For use in research applications. |
| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human CD200 Protein at 2 Mu g/mL (100 Mu L/well) can bind mouse CD200 R1 with a linear range of 3.9-92.9ng/mL. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Cd200r1 |
| Gene ID: | 57781 |
| Uniprot ID: | MO2R1_MOUSE |
| Immunogen: | Recombinant Mouse CD200R1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr26-Pro238) of mouse CD200R1 (Accession #NP_067300.1) fused with Fc, Avi tag at the C-terminus. |
| Immunogen Region: | Thr26-Pro238 |
| Immunogen Sequence: | TDKNQTTQNNSSSPLTQVNT TVSVQIGTKALLCCFSIPLT KAVLITWIIKLRGLPSCTIA YKVDTKTNETSCLGRNITWA STPDHSPELQISAVTLQHEG TYTCETVTPEGNFEKNYDLQ VLVPPEVTYFPEKNRSAVCE AMAGKPAAQISWSPDGDCVT TSESHSNGTVTVRSTCHWEQ NNVSDVSCIVSHLTGNQSLS IELSRGGNQSLRP |
| Function | Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. |
| Protein Name | Cell Surface Glycoprotein Cd200 Receptor 1Cd200 Cell Surface Glycoprotein ReceptorCell Surface Glycoprotein Ox2 Receptor 1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cell Surface Glycoprotein Cd200 Receptor 1 proteinCd200 Cell Surface Glycoprotein Receptor proteinCell Surface Glycoprotein Ox2 Receptor 1 proteinCd200r1 proteinMox2r proteinOx2r protein |
Information sourced from Uniprot.org
