Mouse CD2 protein (Recombinant) (STJP000393)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encoding extracellular domain of Mouse CD2 (SRBC) including an C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Mouse CD2-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | Cd2 |
| Gene ID | 12481 |
| Uniprot ID | CD2_MOUSE |
| Immunogen | Optimized DNA sequence encoding extracellular domain of Mouse CD2 (SRBC) including an C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | ECD |
Additional Info
| Tissue Specificity | Detected in thymus and spleen. |
| Post Translational Modifications | N-glycosylated. |
| Function | CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. |
| Protein Name | T-Cell Surface Antigen Cd2Lfa-2Lfa-3 ReceptorLymphocyte Antigen 37Ly-37T-Cell Surface Antigen T11/Leu-5Cd Antigen Cd2 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | T-Cell Surface Antigen Cd2 proteinLfa-2 proteinLfa-3 Receptor proteinLymphocyte Antigen 37 proteinLy-37 proteinT-Cell Surface Antigen T11/Leu-5 proteinCd Antigen Cd2 proteinCd2 proteinLy-37 protein |
Information sourced from Uniprot.org