Mouse CCL3/MIP-1 alpha protein (Recombinant) (C-His) (STJP020056)
SPECIFICATIONS
HostCHO Cells
ConjugationUnconjugated
ImmunogenRecombinant Mouse CCL3/MIP-1 alpha Protein is produced by CHO cells expression system. The target protein is expressed with sequence (Ala24-Ala92) of Mouse CCL3/MIP-1 alpha (Accession # NP_035467.1) fused with His tag at the C-terminus.
General Information
| Short Description | Recombinant-Mouse CCL3/MIP-1 alpha-C-His protein was developed in cho cells using the region Ala24-Ala92. For use in research applications. |
| Host | CHO Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from 0.22 Mu m filtered solution in 50mM Acetate-sodium acetate pH3.6. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.01 EU/Mu g of the protein by LAL method |
Target Information
| Gene Symbol | Ccl3 |
| Gene ID | 20302 |
| Uniprot ID | CCL3_MOUSE |
| Immunogen | Recombinant Mouse CCL3/MIP-1 alpha Protein is produced by CHO cells expression system. The target protein is expressed with sequence (Ala24-Ala92) of Mouse CCL3/MIP-1 alpha (Accession # NP_035467.1) fused with His tag at the C-terminus. |
| Immunogen Region | Ala24-Ala92 |
| Immunogen Sequence | APYGADTPTACCFSYSRKIP RQFIVDYFETSSLCSQPGVI FLTKRNRQICADSKETWVQE YITDLELNA |
Additional Info
| Tissue Specificity | Expressed in lung, spleen, and pancreas. |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3Heparin-Binding Chemotaxis ProteinL2g25bMacrophage Inflammatory Protein 1-AlphaMip-1-AlphaSis-AlphaSmall-Inducible Cytokine A3Ty-5 |
| Database Links | Reactome: R-MMU-380108 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 3 proteinHeparin-Binding Chemotaxis Protein proteinL2g25b proteinMacrophage Inflammatory Protein 1-Alpha proteinMip-1-Alpha proteinSis-Alpha proteinSmall-Inducible Cytokine A3 proteinTy-5 proteinCcl3 proteinMip1a proteinScya3 protein |
Information sourced from Uniprot.org