Mouse CACNa1B (Calcium Channel, Voltage Dependent, N-Type, Alpha 1B Subunit) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014008)
SPECIFICATIONS
General Information
| Short Description | This CACNa1B Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.053ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Cacna1b |
| Gene ID | 12287 |
| Uniprot ID | CAC1B_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Widespread expression throughout the brain. Highest levels in pyramidal cell layers C1, C2 and C3 of the hippocampus, in the dentate gyrus, in the cortex layers 2 et 4, in the subiculum and the habenula. |
| Post Translational Modifications | Phosphorylated in vitro by CaM-kinase II, PKA, PKC and CGPK. |
| Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. Mediates Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals. |
| Protein Name | Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1bBrain Calcium Channel IiiBiiiCalcium Channel - L Type - Alpha-1 Polypeptide Isoform 5Voltage-Gated Calcium Channel Subunit Alpha Cav2.2 |
| Database Links | Reactome: R-MMU-112308 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative ELISA Names | Voltage-Dependent N-Type Calcium Channel Subunit Alpha-1b ELISA kitBrain Calcium Channel Iii ELISA kitBiii ELISA kitCalcium Channel - L Type - Alpha-1 Polypeptide Isoform 5 ELISA kitVoltage-Gated Calcium Channel Subunit Alpha Cav2.2 ELISA kitCacna1b ELISA kitCach5 ELISA kitCacnl1a5 ELISA kitCchn1a ELISA kit |
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Information sourced from Uniprot.org