Mouse BAFF/CD257 (Tumor Necrosis Factor Ligand Superfamily Member 13b) Antibody Pair (STJAP00564)
General Information
| Short Description | This BAFF/CD257 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
| Determination Method | Colormetric |
Target Information
| Gene Symbol | Tnfsf13b |
| Gene ID | 24099 |
| Uniprot ID | TN13B_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse BAFF/CD257 protien.Detection Immunogen: Recombinant Mouse BAFF/CD257 protien. |
| Sample Type | Serum, plasma and other biological fluids |
Additional Info
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. Isoform 2 is not efficiently shed from the membrane unlike isoform 1. |
| Function | Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Isoform 2 seems to inhibit isoform 1 secretion and bioactivity. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 13bB-Cell-Activating FactorBaffCd Antigen Cd257 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 13b - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 13b - Soluble Form |
| Database Links | Reactome: R-MMU-5668541Reactome: -MMU-5669034Reactome: -MMU-5676594 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinTumor Necrosis Factor Ligand Superfamily Member 13bSoluble Form: Secreted |
| Alternative Antibody Pair Names | Tumor Necrosis Factor Ligand Superfamily Member 13b antibody pairB-Cell-Activating Factor antibody pairBaff antibody pairCd Antigen Cd257 Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 13b - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 13b - Soluble Form antibody pairTnfsf13b antibody pairBaff antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse BAFF/CD257 (Tumor Necrosis Factor Ligand Superfamily Member 13b) Antibody Pair (STJAP00564)
This antibody pair detects mouse BAFF/CD257, also known as Tumor Necrosis Factor Ligand Superfamily Member 13b (UniProt Q9WU72). It is validated for reactivity in mouse samples only.
Both antibodies are goat-derived and antigen affinity purified, supplied at 0.5 mg/mL. The capture antibody is unconjugated, formulated in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.5, while the detection antibody is biotinylated and formulated in PBS with 0.04% Proclin 300, 1% protective protein, and 50% glycerol at pH 7.5.
This pair has been validated for use in ELISA. No other assay formats are listed in the product specifications.
According to the product details, compatible sample types include serum, plasma, and other biological fluids from mouse origin.
Both the capture and detection antibodies were raised against recombinant mouse BAFF/CD257 protein. Both are antigen affinity purified.
Both components should be stored at -20 degrees Celsius for long-term storage. Freeze-thaw cycles should be avoided to maintain reagent integrity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.