Mouse ATP1b1 (ATPase, Na+/K+ Transporting Beta 1 Polypeptide) Sandwich ELISA Kit (STJE0007376)
SPECIFICATIONS
General Information
| Short Description | This ATP1b1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.068ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Atp1b1 |
| Gene ID | 11931 |
| Uniprot ID | AT1B1_MOUSE |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in cardiac muscle and in flexor digitorum brevis (FDB) muscle (at protein level). Expressed in a circadian manner in the kidney and aorta (at protein level). |
| Post Translational Modifications | Glutathionylated. N-glycosylated. |
| Function | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Involved in cell adhesion and establishing epithelial cell polarity. |
| Protein Name | Sodium/Potassium-Transporting Atpase Subunit Beta-1Sodium/Potassium-Dependent Atpase Subunit Beta-1 |
| Database Links | Reactome: R-MMU-210991Reactome: -MMU-5578775Reactome: -MMU-936837 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinApical Cell MembraneSarcolemmaColocalizes With Obscn At The Intercalated Disk And Sarcolemma In CardiomyocytesLocalizes In Long Striations At The Level Of Z And M Lines |
| Alternative ELISA Names | Sodium/Potassium-Transporting Atpase Subunit Beta-1 ELISA kitSodium/Potassium-Dependent Atpase Subunit Beta-1 ELISA kitAtp1b1 ELISA kitAtp4b ELISA kit |
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Information sourced from Uniprot.org