This Ang-2 Competitive ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma and other biological fluids.
Applications
ELISA
Reactivity
Mouse
Sensitivity
9.38pg/mL
Detection Limit
15.63~1000pg/mL
Note
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Product Properties
Storage Instruction
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
This kit recognizes Mouse Ang-2 in samples. No significant cross-reactivity or interference between Mouse Ang-2 and analogues was observed.
Sample Type
Serum, plasma and other biological fluids
Additional Info
Function
Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: Acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Acts by binding to angiotensin receptors AGTR1 and AGTR2. Also binds the DEAR/FBXW7-AS1 receptor. Angiotensin-3: Stimulates aldosterone release. Angiotensin 1-7: Is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.
Protein Name
AngiotensinogenSerpin A8 Cleaved Into - Angiotensin-1Angiotensin 1-10Angiotensin IAng I - Angiotensin-2Angiotensin 1-8Angiotensin IiAng Ii - Angiotensin-3Angiotensin 2-8Angiotensin IiiAng IiiDes-Asp1-Angiotensin Ii - Angiotensin-4Angiotensin 3-8Angiotensin IvAng Iv - Angiotensin 1-9 - Angiotensin 1-7 - Angiotensin 1-5 - Angiotensin 1-4
Cellular Localisation
Secreted
Alternative ELISA Names
Angiotensinogen ELISA kitSerpin A8 Cleaved Into - Angiotensin-1 ELISA kitAngiotensin 1-10 ELISA kitAngiotensin I ELISA kitAng I - Angiotensin-2 ELISA kitAngiotensin 1-8 ELISA kitAngiotensin Ii ELISA kitAng Ii - Angiotensin-3 ELISA kitAngiotensin 2-8 ELISA kitAngiotensin Iii ELISA kitAng Iii ELISA kitDes-Asp1-Angiotensin Ii - Angiotensin-4 ELISA kitAngiotensin 3-8 ELISA kitAngiotensin Iv ELISA kitAng Iv - Angiotensin 1-9 - Angiotensin 1-7 - Angiotensin 1-5 - Angiotensin 1-4 ELISA kitAgt ELISA kitSerpina8 ELISA kit
Specificity
This kit recognizes Ang-Ⅱ in samples. No significant cross-reactivity or interference between Ang-Ⅱ and analogues was observed.
