This AIMP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids..
Applications
ELISA
Reactivity
Mouse
Sensitivity
14.8pg/mL
Detection Limit
31.2-2000pg/mL
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Storage Instruction
The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
serum, plasma, tissue homogenates or other biological fluids.
Additional Info
Tissue Specificity
Highly expressed in salivary glands and pancreatic alpha cells in the adult (at protein level). In the embryo, expressed primarily at sites of tissue remodeling such as ganglia, developing bones and teeth.
Post Translational Modifications
Cleaved by caspase-7 in response to apoptosis to produce EMAP-II.
Function
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
Protein Name
Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 1Multisynthase Complex Auxiliary Component P43 Cleaved Into - Endothelial Monocyte-Activating Polypeptide 2Emap-2Endothelial Monocyte-Activating Polypeptide IiEmap-IiSmall Inducible Cytokine Subfamily E Member 1
NucleusCytoplasmCytosolSecretedEndoplasmic ReticulumGolgi ApparatusEnriched In Secretory Vesicles Of Pancreatic Alpha Cells And Secreted From The Pancreas In Response To Low Glucose LevelsSecreted In Response To HypoxiaAlso Secreted In Response To Both Apoptotic And Necrotic Cell Death
Alternative ELISA Names
Aminoacyl Trna Synthase Complex-Interacting Multifunctional Protein 1 ELISA kitMultisynthase Complex Auxiliary Component P43 Cleaved Into - Endothelial Monocyte-Activating Polypeptide 2 ELISA kitEmap-2 ELISA kitEndothelial Monocyte-Activating Polypeptide Ii ELISA kitEmap-Ii ELISA kitSmall Inducible Cytokine Subfamily E Member 1 ELISA kitAimp1 ELISA kitEmap2 ELISA kitScye1 ELISA kit
