Mouse ACP3 (ACP3) Antibody Pair (STJAP00983)

SPECIFICATIONS
HostRabbit/Rabbit
ConjugationUnconjugated/Biotin
STJAP00983-50
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General Information

Short DescriptionThis ACP3 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA.
ApplicationsELISA
HostRabbit/Rabbit
ReactivityMouse
NoteFOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Product Properties

ConjugationUnconjugated/Biotin
Concentration0.5 mg/mL/0.5-4ug/mL
Dilution Range1:1000-1:10000
Storage InstructionStore at-20°C for the long term, and avoid freeze-thaw cycles.
DetectionColorimetric method;ELISA;Sandwich

Target Information

Gene SymbolAcp3
Gene ID56318
Uniprot IDPPAP_MOUSE
Sample TypeSerum, plasma and other biological fluids

Additional Info

Function A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: In addition to its tyrosine phosphatase activity, also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons. Generates adenosine from AMP. This extracellular adenosine leads to a decrease in chronic pain by activating A1R in nociceptive neurons.
Protein Name Prostatic Acid Phosphatase
5'-Nucleotidase
5'-Nt
Acid Phosphatase 3
Ecto-5'-Nucleotidase
Fluoride-Resistant Acid Phosphatase
Frap
Protein Tyrosine Phosphatase Acp3
Thiamine Monophosphatase
Tmpase
Database Links Reactome: R-MMU-6798695
Cellular Localisation Isoform 1: Secreted
Isoform 2: Cell Membrane
Single-Pass Type I Membrane Protein
Lysosome Membrane
Appears To Shuttle Between The Cell Membrane And Intracellular Vesicles
Colocalizes With Flot1 At Cell Membrane And In Intracellular Vesicles
Colocalizes With Lamp2 On The Lysosome Membrane
Alternative Antibody Pair Names Prostatic Acid Phosphatase antibody pair
5'-Nucleotidase antibody pair
5'-Nt antibody pair
Acid Phosphatase 3 antibody pair
Ecto-5'-Nucleotidase antibody pair
Fluoride-Resistant Acid Phosphatase antibody pair
Frap antibody pair
Protein Tyrosine Phosphatase Acp3 antibody pair
Thiamine Monophosphatase antibody pair
Tmpase antibody pair
Acp3 antibody pair
Acpp antibody pair

Information sourced from Uniprot.org

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