MINPP1 Blocking Peptide for STJ501756 peptide (STJ504371)

SKU:
STJ504371-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: MINPP1 Blocking Peptide for STJ501756 is synthetically produced from the 1-100 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: MINPP1
Gene ID: 9562
Uniprot ID: MINP1_HUMAN
Immunogen Region: 1-100
Specificity: This blocking peptide is recommended for use in combination with MINPP1 antibody, STJ501756
Immunogen: Synthetic peptide taken within amino acid region 1-100 on rat MINPP1 protein
Function Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy. Through the regulation of intracellular inositol polyphosphates, may control intracellular cation homeostasis, including that of calcium and iron, hence affecting free cation availability required for neural cell signaling.
Peptide Name Multiple Inositol Polyphosphate Phosphatase 1
2 -3-Bisphosphoglycerate 3-Phosphatase
2 -3-Bpg Phosphatase
Inositol
1 -3 -4 -5-Tetrakisphosphate 3-Phosphatase
Ins(1 -3 -4 -5p(4 3-Phosphatase
Database Links Reactome: R-HSA-1855231
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Peptide Names Multiple Inositol Polyphosphate Phosphatase 1 protein
2 -3-Bisphosphoglycerate 3-Phosphatase protein
2 -3-Bpg Phosphatase protein
Inositol protein
1 -3 -4 -5-Tetrakisphosphate 3-Phosphatase protein
Ins(1 -3 -4 -5p(4 3-Phosphatase protein
MINPP1 protein
MIPP protein
UNQ900 protein
PRO1917 protein

Information sourced from Uniprot.org

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