MC3 Receptor Blocking Peptide peptide (STJ504364)
SPECIFICATIONS
ImmunogenSynthetic peptide corresponding to unique amino acid sequences on MC3r protein.
General Information
| Short Description | MC3 Receptor Blocking Peptide is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | MC1R |
| Gene ID | 4157 |
| Uniprot ID | MSHR_HUMAN |
| Immunogen | Synthetic peptide corresponding to unique amino acid sequences on MC3r protein. |
Additional Info
| Tissue Specificity | Expressed in melanocytes. Expressed in corticoadrenal tissue. |
| Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes. |
| Peptide Name | Melanocyte-Stimulating Hormone ReceptorMsh-RMelanocortin Receptor 1Mc1-R |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418555Reactome: R-HSA-9856649 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Melanocyte-Stimulating Hormone Receptor proteinMsh-R proteinMelanocortin Receptor 1 proteinMc1-R proteinMC1R proteinMSHR protein |
Information sourced from Uniprot.org