KIF13A Positive Control for STJ501535 is synthetically produced from the sequence and is suitable for use in western blot applications.
Applications
WB
Note
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Product Properties
Dilution Range
WB: 1:500
Formulation
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction
Store at-20°C for long term storage. Avoid freeze-thaw cycles.
This is positive control is recommended for use in combination with KIF13A antibody STJ501535.
Additional Info
Tissue Specificity
Widely expressed, with highest levels in heart, brain and skeletal muscle.
Function
Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abscission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
Peptide Name
Kinesin-Like Protein Kif13aKinesin-Like Protein Rbkin
CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMidbodyEndosome MembraneGolgi Apparatus MembraneRecruited To The Midbody During Cytokinesis
Alternative Peptide Names
Kinesin-Like Protein Kif13a proteinKinesin-Like Protein Rbkin proteinKIF13A proteinRBKIN protein
