| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
KIF13A Blocking Peptide for STJ501535 is synthetically produced from the 1700-1800 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
KIF13A |
| Gene ID: |
63971 |
| Uniprot ID: |
KI13A_HUMAN |
| Immunogen Region: |
1700-1800 |
| Specificity: |
This blocking peptide is recommended for use in combination with KIF13A antibody, STJ501535 |
| Immunogen: |
Synthetic peptide taken within amino acid region 1700-1800 on human KIF13A isoform a protein. |
| Tissue Specificity | Widely expressed, with highest levels in heart, brain and skeletal muscle. |
| Function | Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis. |
| Peptide Name | Kinesin-Like Protein Kif13aKinesin-Like Protein Rbkin |
| Database Links | Reactome: R-HSA-390471 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeMidbodyEndosome MembraneGolgi Apparatus MembraneRecruited To The Midbody During Cytokinesis |
| Alternative Peptide Names | Kinesin-Like Protein Kif13a proteinKinesin-Like Protein Rbkin proteinKIF13A proteinRBKIN protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
