KDM4C/GASC1/JMJD2C Blocking Peptide peptide (STJ504275)

Name: KDM4C/GASC1/JMJD2C Blocking Peptide peptide (STJ504275)
SKU: STJ504275-250
Price: 260.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ImmunogenSynthetic peptide taken within amino acid region 500-520 on human JmjC domain-containing histone demethylation protein 3C protein.

STJ504275-250

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Short Description	KDM4C/GASC1/JMJD2C Blocking Peptide is synthetically produced from the 500-520 sequence and is suitable for use in western blot applications.
Applications	Immunodepletion/Immunocompetition
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Formulation	Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	KDM4C
Gene ID	23081
Uniprot ID	KDM4C_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 500-520 on human JmjC domain-containing histone demethylation protein 3C protein.
Immunogen Region	500-520

Tissue Specificity	Overexpressed in several esophageal squamous cell carcinomas (ESCs).
Function	Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Peptide Name	Lysine-Specific Demethylase 4c Gene Amplified In Squamous Cell Carcinoma 1 Protein Gasc-1 Protein Jmjc Domain-Containing Histone Demethylation Protein 3c Jumonji Domain-Containing Protein 2c Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c
Database Links	Reactome: R-HSA-3214842 Reactome: R-HSA-5625886
Cellular Localisation	Nucleus
Alternative Peptide Names	Lysine-Specific Demethylase 4c protein Gene Amplified In Squamous Cell Carcinoma 1 Protein protein Gasc-1 Protein protein Jmjc Domain-Containing Histone Demethylation Protein 3c protein Jumonji Domain-Containing Protein 2c protein Histone H3-Trimethyl-L-Lysine(9 Demethylase 4c protein KDM4C protein GASC1 protein JHDM3C protein JMJD2C protein KIAA0780 protein

Information sourced from Uniprot.org