KCNJ5 Blocking Peptide for STJ501172 peptide (STJ504132)
SPECIFICATIONS
ImmunogenSynthetic peptide taken within amino acid region 350-450 on human GIRK4 protein.
General Information
| Short Description | KCNJ5 Blocking Peptide for STJ501172 is synthetically produced from the 350-450 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20ยฐC for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNJ5 |
| Gene ID | 3762 |
| Uniprot ID | KCNJ5_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 350-450 on human GIRK4 protein. |
| Immunogen Region | 350-450 |
| Specificity | This blocking peptide is recommended for use in combination with KCNJ5 antibody, STJ501172 |
Additional Info
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. |
| Peptide Name | G Protein-Activated Inward Rectifier Potassium Channel 4Girk-4Cardiac Inward RectifierCirHeart Katp ChannelInward Rectifier K(+ Channel Kir3.4Irk-4Katp-1Potassium Channel - Inwardly Rectifying Subfamily J Member 5 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | G Protein-Activated Inward Rectifier Potassium Channel 4 proteinGirk-4 proteinCardiac Inward Rectifier proteinCir proteinHeart Katp Channel proteinInward Rectifier K(+ Channel Kir3.4 proteinIrk-4 proteinKatp-1 proteinPotassium Channel - Inwardly Rectifying Subfamily J Member 5 proteinKCNJ5 proteinGIRK4 protein |
Information sourced from Uniprot.org