IQSEC3 Positive Control for STJ501486 peptide (STJ505493)

SPECIFICATIONS
STJ505493-5
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General Information

Short DescriptionIQSEC3 Positive Control for STJ501486 is synthetically produced from the sequence and is suitable for use in western blot applications.
ApplicationsWB
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeWB: 1:500
FormulationProvided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage InstructionStore at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolIQSEC3
Gene ID440073
Uniprot IDIQEC3_HUMAN
SpecificityThis is positive control is recommended for use in combination with IQSEC3 antibody STJ501486.

Additional Info

Tissue Specificity Expressed specifically in the adult brain, predominantly in the cerebral cortex and the olfactory bulb, but not in the fetal brain. Expressed only in mature neurons, but not in undifferentiated neural stem precursor cells (NSPCs), nor in glioma cells.
Function Acts as a guanine nucleotide exchange factor (GEF) for ARF1.
Peptide Name Iq Motif And Sec7 Domain-Containing Protein 3
Database Links Reactome: R-HSA-9768919
Cellular Localisation Cytoplasm
Postsynaptic Density
Alternative Peptide Names Iq Motif And Sec7 Domain-Containing Protein 3 protein
IQSEC3 protein
KIAA1110 protein

Information sourced from Uniprot.org

Citations

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