IKAP Blocking Peptide for STJ501408 peptide (STJ505537)

SKU:
STJ505537-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: IKAP Blocking Peptide for STJ501408 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Elp1
Gene ID: 230233
Uniprot ID: ELP1_MOUSE
Specificity: This blocking peptide is recommended for use in combination with IKAP antibody, STJ501408
Immunogen: Recombinant IkappaB kinase complex-associated protein.
Tissue Specificity In the testis, expression is restricted to germ cells during spermatogenesis with no expression detected in somatic cells such as Sertoli cells or Leydig cells (at protein level). In the ovary, expressed in oocytes of primary, secondary and antral follicles (at protein level). Widely expressed in adult tissues with highest levels in brain and also expressed at all embryonic stages.
Post Translational Modifications Phosphorylated.
Function Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation. ELP1 binds to tRNA, mediating interaction of the elongator complex with tRNA. May act as a scaffold protein that assembles active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK).
Peptide Name Elongator Complex Protein 1
Elp1
Ikappab Kinase Complex-Associated Protein
Ikk Complex-Associated Protein
Cellular Localisation Cytoplasm
Nucleus
Alternative Peptide Names Elongator Complex Protein 1 protein
Elp1 protein
Ikappab Kinase Complex-Associated Protein protein
Ikk Complex-Associated Protein protein
Elp1 protein
Ikap protein
Ikbkap protein

Information sourced from Uniprot.org

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