IBP160 Positive Control peptide (STJ503699)

SPECIFICATIONS
STJ503699-5
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General Information

Short DescriptionIBP160 Positive Control is synthetically produced from the sequence and is suitable for use in western blot applications.
ApplicationsWB
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeWB: 1:500
FormulationProvided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage InstructionStore at-20°C for long term storage. Avoid freeze-thaw cycles.

Target Information

Gene SymbolAQR
Gene ID9716
Uniprot IDAQR_HUMAN

Additional Info

Function Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro).
Peptide Name Rna Helicase Aquarius
Intron-Binding Protein Of 160 Kda
Ibp160
Database Links Reactome: R-HSA-6781823
Reactome: R-HSA-6781827
Reactome: R-HSA-6782135
Reactome: R-HSA-6782210
Reactome: R-HSA-72163
Cellular Localisation Nucleus
Nucleoplasm
Localizes To Speckle-Like Regions Of The Nucleoplasm
Alternative Peptide Names Rna Helicase Aquarius protein
Intron-Binding Protein Of 160 Kda protein
Ibp160 protein
AQR protein
KIAA0560 protein

Information sourced from Uniprot.org

Citations

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