Human ZP3 protein (Recombinant) (N-His) (STJP010884)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ZP3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ZP3 |
| Gene ID | 7784 |
| Uniprot ID | ZP3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr171-Gly363 |
Additional Info
| Post Translational Modifications | Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. N-glycosylated. O-glycosylated.removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy. |
| Function | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. |
| Protein Name | Zona Pellucida Sperm-Binding Protein 3Sperm ReceptorZp3a/Zp3bZona Pellucida Glycoprotein 3Zp-3Zona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3 |
| Database Links | Reactome: R-HSA-2534343 |
| Cellular Localisation | Processed Zona Pellucida Sperm-Binding Protein 3: Zona PellucidaCell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Zona Pellucida Sperm-Binding Protein 3 proteinSperm Receptor proteinZp3a/Zp3b proteinZona Pellucida Glycoprotein 3 proteinZp-3 proteinZona Pellucida Protein C Cleaved Into - Processed Zona Pellucida Sperm-Binding Protein 3 proteinZP3 proteinZP3A proteinZP3B proteinZPC protein |
Information sourced from Uniprot.org