Human VWF (Von Willebrand Factor) Antibody Pair (STJAP00179)
SPECIFICATIONS
ClonalityMonoclonal/Monoclonal
HostMouse/Rabbit
ConjugationUnconjugated/Biotin
ImmunogenCapture immunogen: Recombinant Human VWF protein.Detection Immunogen: Recombinant Human VWF protein.
General Information
| Short Description | This VWF antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Mouse/Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Protein A.Detection Purification: Protein A. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | VWF |
| Gene ID | 7450 |
| Uniprot ID | VWF_HUMAN |
| Immunogen | Capture immunogen: Recombinant Human VWF protein.Detection Immunogen: Recombinant Human VWF protein. |
Additional Info
| Post Translational Modifications | All cysteine residues are involved in intrachain or interchain disulfide bonds. N- and O-glycosylated. |
| Function | Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
| Protein Name | Von Willebrand FactorVwf Cleaved Into - Von Willebrand Antigen 2Von Willebrand Antigen Ii |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-140837Reactome: R-HSA-216083Reactome: R-HSA-354192Reactome: R-HSA-354194Reactome: R-HSA-372708Reactome: R-HSA-430116Reactome: R-HSA-5674135Reactome: R-HSA-6802946Reactome: R-HSA-6802948Reactome: R-HSA-6802952Reactome: R-HSA-6802955Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-9649948Reactome: R-HSA-9656223Reactome: R-HSA-9672391Reactome: R-HSA-9672393Reactome: R-HSA-9845619Reactome: R-HSA-9845620Reactome: R-HSA-9845621Reactome: R-HSA-9845622Reactome: R-HSA-9846298 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular MatrixLocalized To Storage Granules |
| Alternative Antibody Pair Names | Von Willebrand Factor antibody pairVwf Cleaved Into - Von Willebrand Antigen 2 antibody pairVon Willebrand Antigen Ii antibody pairVWF antibody pairF8VWF antibody pair |
Information sourced from Uniprot.org