Human Vav-1 protein (Recombinant) (His-Tag) (STJP018524)

Name: Human Vav-1 protein (Recombinant) (His-Tag) (STJP018524)
SKU: STJP018524
Availability: InStock

⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018524

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Short Description	Recombinant-Human Vav-1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.25 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% Glycerol, 2mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	VAV1
Gene ID	7409
Uniprot ID	VAV_HUMAN
Accession Number	NP_005419
Immunogen	Human
Immunogen Region	189-565aa
Immunogen Sequence	MTEYDKR CCCLREIQQT EEKYTDTLGS IQQHFLKPLQ RFLKPQDIEI IFINIEDLLR VHTHFLKEMK EALGTPGAAN LYQVFIKYKE RFLVYGRYCS QVESASKHLD RVAAAREDVQ MKLEECSQRA NNGRFTLRDL LMVPMQRVLK YHLLLQELVK HTQEAMEKEN LRLALDAMRD LAQCVNEVKR DNETLRQITN FQLSIE

Tissue Specificity	Widely expressed in hematopoietic cells but not in other cell types.
Post Translational Modifications	Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN.
Function	Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Protein Name	Proto-Oncogene Vav
Database Links	Reactome: R-HSA-114604 Reactome: R-HSA-1257604 Reactome: R-HSA-1433557 Reactome: R-HSA-193648 Reactome: R-HSA-2029482 Reactome: R-HSA-2219530 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-389359 Reactome: R-HSA-416482 Reactome: R-HSA-4420097 Reactome: R-HSA-512988 Reactome: R-HSA-5218920 Reactome: R-HSA-6811558 Reactome: R-HSA-8980692 Reactome: R-HSA-9013149 Reactome: R-HSA-9013404 Reactome: R-HSA-9013408 Reactome: R-HSA-9027284 Reactome: R-HSA-912631 Reactome: R-HSA-9664422 Reactome: R-HSA-9679191 Reactome: R-HSA-9748787 Reactome: R-HSA-983695
Cellular Localisation
Alternative Protein Names	Proto-Oncogene Vav protein VAV1 protein VAV protein

Information sourced from Uniprot.org